Streicher was a Nazi scientist who originally was tasked with preventing the initial members of the Justice Society from invading his German stronghold. Later on, Helmut disgarded his Murder Machine which was used on that occasion in favor of his own personalized armored uniform. Interestingly, On Earth-One, Ivo used as a mental template for Amazo the German volleyball player Helmut Schultz, who was more a playboy and less a power-mad technologist like that of his Earth-Two twin. That twin, Streicher, would repeatedly match wits against Wonder Woman and her counterpart, then the Amazing Amazon by herself followed by a battle with his lady adversary and the Bombardier on a later occasion. Any future appearances of his are undocumented thus far.
Amazo's agenda was to defeat the newly formed Justice League and, utilizing their replicated abilities, collect seemingly inaccessible ancient objects from around Earth-One from which an immortality serum could be distilled. Red Panzer's agenda was to acquire future technologies, and knowledge using his temporal grappling hook, to gain ultimate power.
Amazo succeeded in providing his master the means to extend his life another 500 years, although the android was himself defeated. Amazo would be redeployed on a few more occasions, twice at the bidding of the Justice League in order to reinvigorate themselves after particularly disheartening attacks by their enemies as well as a pawn of another scientist in T.O. Morrow who was trying to destroy the Justice League. These mirror the Panzer's return engagements versus America's superheroes.
Around the time period that the Panzer debuted, Wonder Woman's All-Star Squadron allies assisted teammate Amazing-Man against another non-living yet sentient being named Real American, completing its master's programming. Just as the All-Stars faced this robot in their world's Detroit, it was the Justice League of Detroit who themselves finally eliminated the threat of Amazo from their world. Real American's existence was briefer than was Amazo's, he was a precursor of the Panzer..
Another robotic rogue on Earth-One was the former Earth-Two hero known as Commander Steel, who tangled with the Justice League and Justice Society. And just as Real American was assembled on Earth-One and lived out its existence on Earth-Two, so too had Commander Steel left his native Earth-Two to live his remaining years on Earth-One.
Two other robots would bedevil these two teams of justice. Criminal scientist Doctor Indrom used the lives of 100 super-villains from across the cosmos to become the core for his World Beater robot, possessing all their superhuman powers. Although initially defeating the Justice League, the Super Friends were able to defeat him by exploiting the weaknesses of the powers the automaton possessed. Then there was Streicher's aforementioned Murder Machine which nearly vanquished Batman, Flash and Green Lantern. While a facsimile of Super-Duper would, like Amazo, be recreated by T.O. Morrow, it ceased to exist... while the Murder Machine apparently was scrapped for parts after World War II.