The Scientific and Technological Advances Research Laboratories, or S.T.A.R. Labs for short, is the preeminent producer of state-of-the-art cutting age technology on Earth-One. Primarily based in Metropolis, with other known branches in New York City and Chicago, several of the professionals there such as Doctor Jenet Klyburn and Doctor Sarah Charles have assisted heroes like Superman and Cyborg in both appraising their abilities and assessing potential threats to mankind.
Another chain of such facilities existed on Earth-Two, tied to like think-tanks around on the world. The principal locale for state-of-the-art technology is Keystone Research Laboratories, Inc. in Keystone City. Founded by Jay Garrick, aka the Flash, he also started a branch laboratory in Flagstaff, Arizona, And no doubt, Jay pooled his labs' own research a time or two with that of fellow Justice Society members such as Rex Tyler...the Hourman...who worked in New York City's Bannermain Chemicals, and at Ultimate Computer Company in Gotham City which employer Karen Starr (Power Girl). These centers of research would aid that world's superheroes just as S.T.A.R. Labs aided Earth-One's.