When Querl Dox of Colu first enlisted in Earth-One's Time Institute, his genius level intellect quickly acquired for him the respect of his peers. Among their many pursuits was developing the Time Bubble that would pierce the time stream and allow them to journey from the 30th century to other eras. Eventually, he became motivated to join the Legion of Super-Heroes as Brainiac Five, coming equipped with his patented force field belt and other gadgets which made as much an impression as fellow recruit Supergirl. His career with this team was mixed, as he was key in several of their victories although he made a misguided attempt to create sentient artificial intelligence which became the evil Computo and later went temporarily mad, almost destroying the universe. He regained his sanity and served the Legion with distinction from them on. Like his counterpart Degaton, Dox was tied to an evil "Brain" in the original Brainiac, as well as coming into conflict with a Legion of All-Stars from time to time.
When Per Degaton, the original version, joined the Time Trust, he was instrumental behind the scenes in its success... and failure. When the Justice Society of America used technology to journey to the 25th century to obtain bomb defense technology, it was Per as a lab assistant that sabotaged it. Some years later, when his supervisor Professor Malachi, several versions of Degaton would attempt to usurp control over the world only to be defeated by the Society and later the All-Star Squadron. While chronal-clones of Degaton had moderate success on at least two occasions of obtaining a rule of decades, the prime version eventually aged and as an old man reunited with fellow Injustice Socialite Brain Wave. In a newly conditioned body, Per's mental acumen allowed him to develop his own force field generator while in conflict with Power Girl and the Society. Eventually, in a rematch with them, he perished in battle.