Wildfire and Shrinking Violet were members of Earth-One's Legion of Super-Heroes in the 30th century. In that same era over in Earth-Two's universe, Don and Betty who were intergalactic pilot. The latter pair journeyed to planet Saro, a world with midgets and giants which they had to contend with. Thanks to his massive atomic gun, Drake was powered to battle any who oppose him. As for Betty, well she had her pluck to help her endure her plight. The last the couple were seen were in a collapsed torture room, where they presumably perished.
For the other Drake, Burroughs was a promising student and lab assistant until an accident with anti-matter rendered his body into a similar mass with explosive power. Housed within his protective uniform, as Wildfire, Drake had vast abilities on par with the most powerful members of the Legion. As for Salu, she inherited the ability that all residents of her planet Imsk to shrink her body mass at will. And at a certain point in her heroic career, she was kidnapped and replaced by a shape shifting actress until she was finally freed and returned to the Legion. Wildfire himself had been separated from the Legion a time or two when his containment suit was destroyed leaving him non-corporeal for a time.