Many are the snakes-in-the-grass whom superheroes have to deal with in their pursuit of truth and justice. In this case, however, the two snakes in question are literally as well as figuratively such that the Scales of Justice have to exact vengeance on these scaly schemers.
Copperhead had established himself as a master criminal in Gotham City which neither the police nor Earth-One's Batman could capture. Using a specialized elastic suit in addition to his agility, this crook seemed out of the Dark Knight's reach, until Batman enlisted the aid of superheroines Wonder Woman and Batgirl in an elaborate... and rather convoluted... strategy to lure the villain into a trap. And eventually, this happened, leading to a lengthy stay in prison for this fanged felon. He would return on a few occasions as a member of the Secret Society of Super-Villains.
Another with a similar fashion sense went by the name of the Snake, seeking to sabotage the Holloway Tunnel defense project by removing its prized workers one-by-one. This drew the interest of reporters Clark Kent and Lois Lane, with the former as Earth-Two's Superman facing the costumed Snake who proved elusive and adaptive enough to evade the Man of Steel's capture three times. Turns out he was in reality disgruntled mine worker Bill Chantey of the Allerton Construction Company who sought revenge for being slighted repeatedly over the years in promotions. Despite trying using his prized pets to eliminate Lois Lane, he was bitten by one of these snakes himself!
In the end, despite their clever ingenuity in designing such slick scaly suits and elaborate snake snares, this pair found that the caped crusaders whom they encountered were superior foes!